![]() If you’re feeling a bit blocked up, try sipping some apple juice. 3. Constipation Relief (Kids and Adults!) Though it’s not necessarily a medically-licensed treatment just yet, it’s shown promising results in certain studies, and it certainly can’t hurt to work a glass or two into your daily diet and see how it helps. 2. Heart-HealthyĪnother great apple juice benefit is that it keeps your veins clean and clear! Apple juice is known for lowering cholesterol, which in turn helps keep your arteries clear, which helps lower your risk for cardiovascular diseases, heart attacks, and strokes. This is why you’ll often see people adding powdered Vitamin C supplements into their juice and other beverages around cold and flu season-it’s one of the most popular defenses against the sniffles out there! It can even help lower your risk of developing cancer, and some studies are looking into its effectiveness when used in tandem with chemotherapy treatments. While Vitamin C serves several purposes in the upkeep of the body and improvement of health, one of the most important functions it performs is the strengthening of the immune system. ![]() Most of us have heard of Vitamin C and know that it’s one of the top-touted vitamins to stay stocked up on, but what exactly does it do? One of the main benefits of apple juice nutrition is consuming Vitamin C. Whether you prefer a glass or a juice box, apple juice is a favorite of people both young and old-but did you know just how many benefits of apple juice you’re enjoying with every sip? If not, no worries-I’ve gathered a list right here for you! Check out 11 apple juice benefits that are sure to amaze you! 11 Apple Juice Benefits 1. (Vitamin) C is for Cancer Prevention! Apple juice-the star of lunch boxes and school cafeteria lunches everywhere! Odds are you spent a good portion of your childhood enjoying this tart, refreshing drink on hot summer afternoons or as a sidekick to your daily breakfast.
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![]() Read more about extending the shelf life of your tape here.ĭid you clean the surface before applying the tape?ĭid you remember to remove the liner? (Yes, that happened!) When materials are bought in bulk and stored in dusty, wet or extremely hot or cold conditions for extended periods, the adhesive deteriorates. If you leave milk on the counter overnight, it spoils. In this scenario, 1/4” wide might fall, but 1/2″ might do it. Think of it this way: Is there a big enough surface of sticky stuff applied to a substrate to hold the weight of the object stuck to the other side of the tape? Likewise, does the “other side” have a large enough surface of sticky stuff applied to it to hold the weight of the object? For example: If you need to adhere poly sheeting to a wall, you need to have a wide enough strip of double-coated tape to be able to hold the weight of the poly sheeting to the wall. The correct surface contact to weight ratio plays a factor. This will considerably reduce any tendency to migrate, thereby preventing tape failure. When using this type of material, choose a high-quality, double-coated tape specifically designed for PVC applications. ![]() If a typical pressure-sensitive adhesive is applied to PVC and allowed to remain in place for a prolonged period, the plasticizer will migrate from the PVC surface into the pressure-sensitive adhesive making the glue a gummy mess. This movement is known as “migration.”įor example, consider PVC: plasticized to provide flexibility, it is a lower-cost, lower-molecular weight material. Liquids such as oils, plasticizers, and dyes are a lighter weight material and can therefore easily “move” from the product (the surface) to be absorbed by any adjacent material (the tape). ![]() If the area where you will be using the tape sees above-average UV exposure, you may need to consider a different tool for the job. Absolutely not the qualities you want in a tape that needs to hold for any duration in a particular application. Prolonged exposure to ultraviolet light can cause certain chemical materials (such as natural and some synthetic rubbers as well as polyethylene) to become hard and brittle. To prevent tape failure, prepare the surface, give it a quick wash with rubbing alcohol and dry it with a clean cloth. Traces of dust, dirt, grease, and even the slightest hint of moisture before bonding will contaminate the adhesive surface and act as a barrier between the two. If you must work at lower temperatures, then use a temperature-sensitive double-sided tape specifically designed for colder climates. And on the flip side, extremely high temperatures can cause the adhesive to melt and lose its strength. Are both the tape and the surface at least 18✬/65✯? The tackiness of the adhesive tape is very temperature-dependent, and the colder the conditions, the weaker the bond will be. When in doubt, test the adhesive first to prevent tape failure.Ĭarefully factor in the temperature. Or, perhaps, it’s too aggressive and caused damage to the surface it was applied to. Maybe the one you chose isn’t aggressive enough and it fell off. Not all double-sided tapes are created equal. ![]() The package label made lofty promises, but generally speaking, adhesive testing should always be done before using double-sided tape. Here are the 8 most common reasons your double-sided tape won’t stick and how to prevent tape failure. It’s easy to assume the tape itself is to blame, but truth be told, there are some other usual suspects to consider first. Heavy-duty double-sided tape is useful in a wide range of construction scenarios, but no tool is perfect for every job. McAfee's malware detection has improved greatly in the past couple of years, but it's still not quite top-of-the-line.ĭespite that, the entry-level McAfee AntiVirus Plus is a bargain: $60 per year buys software for up to 10 (in practice, unlimited) devices, whether they run Windows, macOS, iOS or Android, and the software comes with a file shredder and a two-way firewall. Read our full Kaspersky Total Security review. We think it's the best antivirus software you can buy today. The premium antivirus suite, Kaspersky Total Security (£19.99 UK/$44.99 US), adds backup software, parental controls, file encryption, a file shredder and an unlimited password manager. It also includes software for macOS, Android and iOS. It has a secure browser, anti-theft protection for laptops, webcam protection and a limited-use VPN client that kicks in when you connect to an open Wi-Fi network. Kaspersky Internet Security (£17.49 UK/$39.99 US) is our top choice among midrange packages. But it's beaten by Bitdefender Antivirus Plus, which has even more features. The entry-level program, Kaspersky Anti-Virus (starting at £12.49 UK/$29.99 US), has dedicated ransomware protection, a virtual keyboard and a convenient online account portal. Kaspersky's Windows products have excellent malware-detection scores and a light-to-moderate system-performance impact, the two most important criteria in our rankings. ![]() Read our full Bitdefender Antivirus Plus review. The midrange Bitdefender Internet Security adds parental controls, webcam protection and a two-way firewall, while Bitdefender Total Security tops off the lineup with an anti-theft feature for laptops, a system optimizer and licenses for Bitdefender Antivirus for Mac and Bitdefender Mobile Security for Android.Ī fourth product, Bitdefender Premium Security, is basically Total Security with unlimited VPN usage, a cross-platform password manager and priority tech support.īut the best deal is the Bitdefender Family Pack, which puts Total Security on up to 15 devices for (a frequently discounted) $120 per year.Īs mentioned above, Bitdefender Total Security has merited a Highly Recommended mention for Best Antivirus Software in the Tom's Guide Awards. It also offers the most value, with an unlimited (but Windows-only) password manager, a secure browser with a virtual keyboard, a Wi-Fi network scanner, a file shredder, protection against encrypting ransomware and Bitdefender's web-privacy software - features often found only with pricier antivirus packages. Its active scans don't add much to the background system impact, but that background load is a bit heavy. ![]() It has very good, if not perfect, malware-detection scores. Bitdefender Antivirus Plus is our top choice among entry-level antivirus products. ![]() The trees were visualized in Figtree ( Rambaut, 2018). A maximum likelihood phylogenetic tree, 1000 bootstrap replicates were constructed in PhyML ( Guindon and Gascuel, 2003 Lemoine et al., 2018) and a Bayesian tree using MrBayes ( Ronquist and Huelsenbeck, 2003) were constructed. The alignment was manually edited until a codon alignment was attained in all coding sequences (CDS). The 431 reference WGS were aligned with MUSCLE ( Edgar, 2004). The SARS-CoV-2 data generators are properly acknowledged in the acknowledgements section of this article and detailed information is provided in Supplementary Table S1. The SARS-CoV-2 sequences were downloaded from the GISAID database ( ) together with annotation of its original location, collection date and originating and submitting laboratory. To this reference dataset, we added 47 whole genomes of the current Coronavirus 2019 (SARS-CoV-2) outbreak that originated in Wuhan, China, in December 2019. These included 132 sequences of Severe Acute Respiratory Syndrome related Coronavirus (SARSr-CoV), 121 sequences of Beta coronavirus, 97 sequences of Middle East Respiratory Syndrome related Coronavirus (MERSr-CoV), 19 sequences of Human Coronavirus HKU1, 9 sequences of Murine Hepatitis Virus, 4 of Rousettus Bat Coronavirus HKU9, 3 of Rat Coronavirus and 1 WGS of Tylonycteris Bat Coronavirus HKU4, Zaria_bat_coronavirus and Longquan Rl Rat coronavirus. ![]() The tool also identifies changes at nucleotides, coding regions and proteins using a novel dynamic aligner to allow tracking new viral mutations ( Fig. 1).Ī reference dataset of previously published coronavirus whole-genome sequences (WGS) was compiled from the Virus Pathogen Resource (VIPR) database ( This dataset consisted of 386 WGS of nine important coronavirus species. The Genome Detective Coronavirus Typing Tool is a free-of-charge web-based bioinformatics pipeline that can accurately and quickly identify, assemble and classify coronaviruses genomes. Here, we present a new contribution that can speed up this communal effort. This has helped the understanding of the transmission dynamics, the development of rapid diagnostic and has informed public health response. They have openly and rapidly shared genomic and clinical data as never seen before allowing research results to be released almost instantaneously. This coronavirus outbreak has been unprecedented so too is the way that the scientific community has responded to it. It has high fatality rate ( Huang et al., 2020), can be transmitted from person to person, has infected over 70 000 individuals and has spread to over 30 countries in less than 2 months ( WHO, 2020). It causes severe respiratory illness, which the WHO recently named COVID-19 disease. ![]() The virus is a SARS-related coronavirus (SARSr-CoV), and it is genetically associated with SARSr-CoV strains that infect bats in China ( Lu et al., 2020 Zhu et al., 2020). The novel coronavirus (SARS-CoV-2), first isolated in Wuhan, China, has already caused more infections than the previous severe acute respiratory syndrome (SARS) outbreak of 20. In the end of January 2020, the WHO has declared it a global emergency ( WHO, 2020). We are currently faced with a potential global epidemic of a new coronavirus that has infected thousands of people in China and is spreading rapidly around the world. The tool also allows tracking of new viral mutations as the outbreak expands globally, which may help to accelerate the development of novel diagnostics, drugs and vaccines to stop the COVID-19 disease. The tool has been tested and validated with hundreds of whole genomes from 10 coronavirus species, and correctly classified all of the SARS-related coronavirus (SARSr-CoV) and all of the available public data for SARS-CoV-2. The tool can accept up to 2000 sequences per submission and the analysis of a new whole-genome sequence will take approximately 1 min. Here, we present the Genome Detective Coronavirus Typing Tool that can accurately identify the novel severe acute respiratory syndrome (SARS)-related coronavirus (SARS-CoV-2) sequences isolated in China and around the world. Since its release in 2019, we have produced a number of typing tools for emergent viruses that have caused large outbreaks, such as Zika and Yellow Fever Virus in Brazil. ![]() This application allows the identification of phylogenetic clusters and genotypes from assembled genomes in FASTA format. Genome detective is a web-based, user-friendly software application to quickly and accurately assemble all known virus genomes from next-generation sequencing datasets. |
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